| Item | Clone | Isotype | Cellular expression | Downloads |
|---|---|---|---|---|
| CD8 | MCD8 | Mo IgG1 | T cytotoxic/suppressor cells, NK cells | Product Info Sheet Product Info Sheet (Italian) |
The MCD8 antigen is present on most thymocytes, T cytotoxic/suppressor cells and a subpopulation of NK cells.
MCD8 acts as a co-receptor with the TcR in recognizing antigens presented by MHC Class I and plays a role in the T cell-mediated immune response. MCD8 is commonly used in routine immunophenotyping, the determination of CD4/CD8 ratios in HIV/AIDS patients and aids in the identification of T cell leukemias (common T-ALL or mature T-ALL)s. MCD8 also distinguishes between chronic B and T cell lymphoid leukemias.
| Name | Code 100 tests | Regulatory Status |
|---|---|---|
| Purified | • IQP-104P | |
| FITC | • IQP-104F | IVD/CE |
| R-PE | • IQP-104R | IVD/CE |
| CyQ | • IQP-104C | IVD/CE |
| APC | • IQP-104A | IVD/CE |
| PerCP | • IQP-104PC | |
| PerCPCy5.5 |
