Pregnostic®-PE Ip

A kit for the measurement of plasma ESM-1 concentrations

Special features

  • Complete ELISA kit with pre-coated plates
  • Rapid assay, takes less than 3 hours, less than 1 hour of hands-on-time
  • Quantification of the ESM-1 in biological fluids (sera, plasma) or in human cell culture supernatants
  • Ready to use assay
  • For research use only. Not for use in diagnostic procedures.

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If you are interested in the Pregnostic®-PE Ip for research purposes in cooperation with IQ Products, please contact us!

Introduction

Endothelial cell-specific molecule (ESM-1) is a unique biomarker of vascular endothelial activation/dysfunction in diseases. The variation of blood levels of ESM-1 may reflect endothelial dysfunction in several pathological conditions, including sepsis, cancer, dengue fever and obesity 1. Higher ESM-1 levels are also related to occurrence of pre-eclampsia in pregnancy 2-6.

Recently IQ Products’ Research and Development team published, in cooperation with the University Medical Center Groningen (The Netherlands), their findings of the ESM-1 plasma levels during uncomplicated and pre-eclamptic pregnancies in Pregnancy Hypertension.

Product specifications

Pregnostic®-PE Ip contains all components required for quantification of human ESM-1 in cell culture supernatants, serum or plasma. This human Pregnostic®-PE Ip ELISA set uses the robust and well-described quantitative sandwich immunoassay technique. The kit is available for research purposes. The performance characteristics of this kit have not completely established yet.

References:

  1. Sarrazin et al. (2010) J Cancer Sci. Ther. 2: 47-52
  2. Schuitemaker et al. (2018) Pregnancy Hypertens. Mar 1;12:58-64
  3. Chang et al. (2015)  Int J Clin Exp Pathol. 8(11): 14733-14740
  4. Adekola et al. (2015) J Matern Fetal Neonatal Med. 28(14):1621-1632
  5. Cakmak et al. (2016) Clin Exp Hypertens. 38(2): 137-142
  6. Hentschke et al. (2015) 74: 152-156

Safety Data Sheet

SDS

Package Insert

English

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The Netherlands

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